Hypertension and cerebral blood flow in the development of Alzheimer's disease,Alzheimer's & Dementia

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Hypertension and cerebral blood flow in the development of Alzheimer's disease
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-09-10 , DOI: 10.1002/alz.14233
Dario Bachmann _{1,

2} , Antje Saake ₁ , Sandro Studer ₁ , Andreas Buchmann ₁ , Katrin Rauen _{1,

3,

4} , Esmeralda Gruber ₁ , Lars Michels ₅ , Roger M Nitsch _{1,

6} , Christoph Hock _{1,

6} , Anton Gietl _{1,

3} , Valerie Treyer _{1,

7} ,

Affiliation

We investigated the interactive associations between amyloid and hypertension on the entorhinal cortex (EC) tau and atrophy and the role of cerebral blood flow (CBF) as a shared mechanism by which amyloid and hypertension contribute to EC tau and regional white matter hyperintensities (WMHs).

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