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The inflammaging clock strikes IL-11!
Immunity ( IF 25.5 ) Pub Date : 2024-09-10 , DOI: 10.1016/j.immuni.2024.08.010 Saad Khan 1 , Veronica Chang 2 , Daniel A Winer 3
中文翻译:
发炎的时钟敲响了 IL-11!
更新日期:2024-09-10
Immunity ( IF 25.5 ) Pub Date : 2024-09-10 , DOI: 10.1016/j.immuni.2024.08.010 Saad Khan 1 , Veronica Chang 2 , Daniel A Winer 3
Affiliation
Chronic inflammation is considered a hallmark of aging. In a recent issue of Nature, Widjaja et al. examined genetic and pharmacologic inhibition of interleukin (IL)-11 on aging pathology and found that inhibiting IL-11 signaling increases lifespan and healthspan in mice.
中文翻译:
发炎的时钟敲响了 IL-11!
慢性炎症被认为是衰老的标志。在最近一期的《自然》杂志上,Widjaja 等人研究了白细胞介素 (IL)-11 对衰老病理学的遗传和药理学抑制,发现抑制 IL-11 信号传导可延长小鼠的寿命和健康寿命。