Prostate Cancer Diagnosis and Treatment Enhancement through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer. PIONEER brings together 34 private and public stakeholders from 9 countries in one multidisciplinary research consortium with the aim of positively transforming the field of prostate cancer clinical care by answering pressing questions related to prostate cancer screening, diagnosis and treatment. PIONEER has developed a unique state-of-the-art big data analytic platform by integrating existing data sources from patients with prostate cancer. PIONEER leveraged this platform to address prioritized research questions, filling knowledge gaps in the characterization, management and core outcomes of prostate cancer across the different disease stages. The network has benefited from sustained patient and stakeholder involvement and engagement, but many challenges remain when using real-world data for big data projects. To continue to advance prostate cancer care, data need to be available, suitable methodologies should be selected and mechanisms for knowledge sharing must be in place. Now acting as the prostate cancer arm of the European Association of Urology’s new endeavour, UroEvidenceHub, PIONEER maintains its goal of maximizing the potential of big data to improve prostate cancer care.

欧洲通过大数据的力量增强前列腺癌诊断和治疗 (PIONEER) 是欧洲前列腺癌大数据卓越网络。 PIONEER 将来自 9 个国家的 34 个私人和公共利益相关者聚集在一个多学科研究联盟中，旨在通过回答与前列腺癌筛查、诊断和治疗相关的紧迫问题，积极改变前列腺癌临床护理领域。 PIONEER 通过整合前列腺癌患者的现有数据源，开发了一个独特的、最先进的大数据分析平台。 PIONEER 利用该平台解决优先研究问题，填补不同疾病阶段前列腺癌特征、管理和核心结果方面的知识空白。该网络受益于患者和利益相关者的持续参与和参与，但在将现实世界数据用于大数据项目时仍然存在许多挑战。为了继续推进前列腺癌护理，需要提供数据，选择合适的方法，并且必须建立知识共享机制。 PIONEER 现在作为欧洲泌尿外科协会新项目 UroEvidenceHub 的前列腺癌部门，始终坚持其目标：最大限度地发挥大数据的潜力，以改善前列腺癌护理。