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Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma
Developmental Cell ( IF 10.7 ) Pub Date : 2024-09-09 , DOI: 10.1016/j.devcel.2024.07.002 Sara Badodi 1 , Silvia Marino 2
中文翻译:
表观遗传重编程使 NF1A/B 在 SHH 髓母细胞瘤中起致癌作用
更新日期:2024-09-09
Developmental Cell ( IF 10.7 ) Pub Date : 2024-09-09 , DOI: 10.1016/j.devcel.2024.07.002 Sara Badodi 1 , Silvia Marino 2
Affiliation
In this issue of Developmental Cell, Shiraishi et al. investigate the epigenetic changes occurring during the formation of SHH medulloblastoma and show that an epigenomic shift renders Nuclear Factor I family of transcription factors oncogenic.
中文翻译:
表观遗传重编程使 NF1A/B 在 SHH 髓母细胞瘤中起致癌作用
在本期《发育细胞》中,Shiraishi 等人研究了 SHH 髓母细胞瘤形成过程中发生的表观遗传变化,并表明表观基因组变化使转录因子的核因子 I 家族致癌。