Association between early airway intervention in the pre-hospital setting and outcomes in out of hospital cardiac arrest patients: A post-hoc analysis of the Target Temperature Management-2 (TTM2) trial,Resuscitation

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Association between early airway intervention in the pre-hospital setting and outcomes in out of hospital cardiac arrest patients: A post-hoc analysis of the Target Temperature Management-2 (TTM2) trial
Resuscitation ( IF 6.5 ) Pub Date : 2024-09-05 , DOI: 10.1016/j.resuscitation.2024.110390
Denise Battaglini ₁ , Irene Schiavetti ₂ , Lorenzo Ball ₁ , Janus Christian Jakobsen ₃ , Gisela Lilja ₄ , Hans Friberg ₅ , Pedro David Wendel-Garcia ₆ , Paul J Young ₇ , Glenn Eastwood ₈ , Michelle S Chew ₉ , Johan Unden ₁₀ , Matthew Thomas ₁₁ , Michael Joannidis ₁₂ , Alistar Nichol ₁₃ , Andreas Lundin ₁₄ , Jacob Hollenberg ₁₅ , Naomi Hammond ₁₆ , Manoj Saxena ₁₇ , Annborn Martin ₁₈ , Miroslav Solar ₁₉ , Fabio Silvio Taccone ₂₀ , Josef Dankiewicz ₂₁ , Niklas Nielsen ₂₂ , Anders Morten Grejs ₂₃ , Matt P Wise ₂₄ , Matthias Hängghi ₂₅ , Ondrej Smid ₂₆ , Nicolò Patroniti ₁ , Chiara Robba ₁ ,

Affiliation

Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genova, Italy; Department of Surgical Science and Integrated Diagnostics (DISC), University of Genoa, Genova, Italy.
Department of Health Sciences, University of Genoa, Genova, Italy.
Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Department of Clinical Sciences Lund, Neurology, Skåne University Hospital, Lund University, Getingevägen 4, 222 41, Lund, Sweden.
Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Lund University, Lund, Sweden.
Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Medical Research Institute of New Zealand, Private Bag 7902, Wellington, 6242, New Zealand; Intensive Care Unit, Wellington Regional Hospital, Wellington, New Zealand; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Critical Care, University of Melbourne, Parkville, VIC, Australia.
Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne Australia; Department of Intensive Care, Austin Hospital, Heidelberg, Australia.
Department of Anaesthesia and Intensive Care, Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Department of Operation and Intensive Care, Lund University, Hallands Hospital Halmstad, Halland, Sweden.
University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University College Dublin-Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland.
Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 423 45, Gothenburg, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Center for Resuscitation Science, Karolinska Institutet, Stockholm, Sweden.
Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Critical Care Division, The George Institute for Global Health, Faculty of Medicine, UNSW Sydney, Sydney, Australia.
Critical Care Division and Department of Intensive Care Medicine, The George Institute for Global Health and St George Hospital Clinical School, University of New South Wales, Sydney, Australia.
Department of Clinical Medicine, Anaesthesiology and Intensive Care, Lund University, Lund, Sweden.
Department of Internal Medicine, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic; Department of Internal Medicine-Cardioangiology, University Hospital Hradec Králové, Hradec Králové, Czech Republic.
Department of Intensive Care Medicine, Université Libre de Bruxelles, Hopital Universitaire de Bruxelles (HUB), Brussels, Belgium.
Department of Clinical Sciences Lund, Cardiology, Skåne University Hospital, Lund University, Lund, Sweden.
Department of Clinical Sciences Lund, Anaesthesia and Intensive Care and Clinical Sciences Helsingborg, Helsingborg Hospital, Lund University, Lund, Sweden.
Department of Intensive Care Medicine, Aarhus University Hospital, Denmark, Department of Clinical Medicine, Aarhus University, Denmark.
Adult Critical Care, University Hospital of Wales, Cardiff, UK.
Department of Intensive Care Medicine, Inselspital, Bern University Hospital University of Bern Bern Switzerland.
2nd Department of Medicine, Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 00, Prague 2, Czech Republic.

Airway management is a critical component of out-of-hospital cardiac arrest (OHCA) resuscitation. The primary aim of this study was to describe pre-hospital airway management in adult patients post-OHCA. Secondary aims were to investigate whether tracheal intubation (TI) versus use of supraglottic airway device (SGA) was associated with patients’ outcomes, including ventilator-free days within 26 days of randomization, 6 months neurological outcome and mortality.

中文翻译：

院前早期气道干预与院外心脏骤停患者结局之间的关联：目标温度管理 2 （TTM2）试验的事后分析

气道管理是院外心脏骤停（OHCA）复苏的关键组成部分。本研究的主要目的是描述 OHCA 后成年患者的院前气道管理。次要目标是调查气管插管（TI）与使用声门上气道装置（SGA）是否与患者的结局相关，包括随机分组后 26 天内无呼吸机的天数、6 个月的神经系统结局和死亡率。

更新日期：2024-09-05

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