Omega-3 Polyunsaturated Fatty Acids as a Protective Factor for Myopia,American Journal of Ophthalmology

当前位置： X-MOL 学术 › Am. J. Ophthalmol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Omega-3 Polyunsaturated Fatty Acids as a Protective Factor for Myopia
American Journal of Ophthalmology ( IF 4.1 ) Pub Date : 2024-09-05 , DOI: 10.1016/j.ajo.2024.08.041
Can Can Xue ₁ , Hengtong Li ₂ , Xing-Xuan Dong ₃ , Marco Yu ₁ , Zhi Da Soh ₄ , Crystal Chong ₁ , Chen Jiang ₅ , Helene Choquet ₅ , Nazlee Zebardast ₆ , Seyedeh Maryam Zekavat ₇ , Pirro G Hysi ₈ , Seang Mei Saw ₉ , Qiao Fan ₁₀ , Yih-Chung Tham ₁₁ , Chen-Wei Pan ₃ , Ching-Yu Cheng ₁₁

Affiliation

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
School of Public Health, Suzhou Medical College of Soochow University, Suzhou, China.
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Division of Research, Kaiser Permanente Northern California (KPNC), Pleasanton, CA, United States.
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States; Program in Medical and Population Genetics, Broad institute of MiT and Harvard, Cambridge, MA, United States.
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States; Program in Medical and Population Genetics, Broad institute of MiT and Harvard, Cambridge, MA, United States; Cardiovascular Research Center, Massachusetts General hospital, Harvard Medical School, Boston, MA, United States.
King's College London, Section of Ophthalmology, School of Life Course Sciences, London, UK; King's College London, Department of Twin Research and Genetic Epidemiology, London, UK; University College London, GOSH Institute of Child Health, London, UK.
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore.

Animal models suggest omega-3 polyunsaturated fatty acids (PUFAs) may protect against myopia by modulating choroidal blood perfusion, but clinical evidence is scarce and mixed. We aimed to determine the causality between omega-3 PUFAs and myopia using Mendelian randomization (MR) analysis.

中文翻译：