Background Since the late 1990s, there has been a worldwide surge of scientific interest in the pre-psychotic phase, resulting in the introduction of several clinical tools for early detection. The predictive accuracy of these tools has been limited, motivating the need for methodological and perspectival improvements. The EASE manual supports systematic assessment of anomalous self-experience, and proposes an overall model of understanding how most psychotic experiences may be initially generated on the basis of a unifying, fundamental, pre-reflective distortion of subjectivity. Study Design The EASE is time-consuming, so in order to spread the use of this essential perspective of psychosis risk we selected prototypical and frequent phenomena from the EASE, combining them into SQuEASE-11. To investigate this instrument for clinical relevance, basic psychometric properties, factor structure, and relationships with gold standard instruments and the full EASE, it was administered as an interview in the STEP intervention trial (Melbourne, Australia), with 328 clinical high-risk for psychosis (CHR-P) patients. Study Results The SQuEASE-11 had moderate internal consistency and revealed two correlated factors. Significant relationships were observed between the SQuEASE-11 and the widely used and validated instruments CAARMS, BPRS, SANS, MADRS, DACOBS, and SOFAS. The correlation with the full EASE was very strong. Conclusions These 11 items do not necessarily relate specifically to ipseity disturbance, but the SQuEASE-11 seems to be a clinically relevant and brief supplementary first-line interview in CHR-P subjects. It may give a qualified indication of the need for a complete EASE interview, and it may also, importantly, inform treatment planning.

中文翻译：

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精神病风险：是时候以实证的方式看待一种经济实用的第一步方法来检查异常的自我体验了。探索 SQuEASE-11


背景 自 20 世纪 90 年代末以来，世界范围内对精神病前期的科学兴趣激增，导致了多种用于早期检测的临床工具的引入。这些工具的预测准确性有限，因此需要改进方法和视角。 EASE手册支持对异常自我体验的系统评估，并提出了一个总体模型来理解大多数精神病体验最初是如何在统一的、基本的、前反思性的主观性扭曲的基础上产生的。研究设计 EASE 非常耗时，因此为了推广精神病风险这一基本观点的使用，我们从 EASE 中选择了典型且常见的现象，并将它们合并到 SQuEASE-11 中。为了调查该工具的临床相关性、基本心理测量特性、因子结构以及与金标准工具和完整 EASE 的关系，在 STEP 干预试验（澳大利亚墨尔本）中进行了访谈，对 328 名临床高风险患者进行了访谈。精神病（CHR-P）患者。研究结果 SQuEASE-11 具有中等内部一致性，并揭示了两个相关因素。在 SQuEASE-11 与广泛使用和验证的仪器 CAARMS、BPRS、SANS、MADRS、DACOBS 和 SOFAS 之间观察到显着的关系。与完整 EASE 的相关性非常强。结论 这 11 项不一定与自体功能障碍具体相关，但 SQuEASE-11 似乎是 CHR-P 受试者的临床相关且简短的补充一线访谈。它可以给出完整 EASE 访谈必要性的合格指示，而且重要的是，它还可以为治疗计划提供信息。