Red-Shifting B12-Dependent Photoreceptor Protein via Optical Coupling for Inducible Living Materials,Angewandte Chemie International Edition

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Red-Shifting B12-Dependent Photoreceptor Protein via Optical Coupling for Inducible Living Materials
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2024-09-06 , DOI: 10.1002/anie.202411105
Hong Kiu Francis Fok ₁ , Xin Dai ₂ , Qikun Yi ₃ , Chi Ming Che ₄ , Lingxiang Jiang ₅ , Liting Duan ₆ , Jinqing Huang ₂ , Zhongguang Yang ₃ , Fei Sun ₇

Affiliation

Red-shifting of B12-dependent photoreceptor CarH_C has been accomplished by labeling with the red light-capturing fluorophore Cy5, which further enables the assembly and disassembly of biomacromolecules or living cells in a B₁₂ and red light-dependent manner. This optical coupling approach can potentially be expanded for spectral tuning of other optogenetic tools.

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