Here we highlight the Alzheimer's Association's role since its inception, as a strategic collaborator with National Institutes of Health–National Institute on Aging in the development of the modern era of the Alzheimer's Movement and in making Alzheimer's disease (AD) a national priority in the United States by developing several initiatives to advance knowledge about the cause, diagnosis, and treatment of dementia. Among these collaborative undertakings, the Alzheimer's Disease Neuroimaging Initiative (ADNI) is an exemplary case, launched with groundwork by the Neuroimaging Working Group sponsored by the Association's Ronald and Nancy Reagan Research Institute on AD. The unique contribution of the Association to the development of ADNI includes participation as a member of ADNI's Private Partner Scientific Board and involvement in developing an AD biomarker standardization and validation subproject, which has led to a conceptual shift in the field to define AD based on its underlying biology. Furthermore, the creation of Worldwide ADNI (WW-ADNI) is highlighted, underscoring the global impact of these efforts.

中文翻译：

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阿尔茨海默病协会在阿尔茨海默病神经影像学计划起源中的作用


在这里，我们强调了阿尔茨海默病协会自成立以来的作用，作为美国国立卫生研究院-国家老龄化研究所的战略合作者，在阿尔茨海默病运动的现代发展中，并通过制定多项举措来促进对阿尔茨海默病 （AD） 的了解，使阿尔茨海默病 （AD） 成为美国的国家优先事项。 痴呆的诊断和治疗。在这些合作项目中，阿尔茨海默病神经影像学倡议 （ADNI） 是一个示范性案例，由该协会的 Ronald 和 Nancy Reagan AD 研究所赞助的神经影像学工作组发起。该协会对 ADNI 发展的独特贡献包括作为 ADNI 私人合作伙伴科学委员会的成员参与并参与开发 AD 生物标志物标准化和验证子项目，这导致了该领域的概念转变，即根据其基础生物学定义 AD。此外，还强调了 Worldwide ADNI （WW-ADNI） 的创建，强调了这些努力的全球影响。