MASLD in people with HIV exhibits higher fibrosis stage despite lower disease activity than in matched controls,Alimentary Pharmacology & Therapeutics

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MASLD in people with HIV exhibits higher fibrosis stage despite lower disease activity than in matched controls
Alimentary Pharmacology & Therapeutics ( IF 6.6 ) Pub Date : 2024-09-05 , DOI: 10.1111/apt.18236
Daniela S Allende ₁ , Oscar Cummings ₂ , Alice L Sternberg ₃ , Cynthia A Behling ₄ , Danielle Carpenter ₅ , Ryan M Gill ₆ , Cynthia D Guy ₇ , Matthew M Yeh ₈ , Samer Gawrieh ₉ , Richard K Sterling ₁₀ , Susanna Naggie ₁₁ , Rohit Loomba ₁₂ , Jennifer C Price ₆ , Mary McLaughlin ₁₃ , Colleen Hadigan ₁₃ , Holly Crandall ₂ , Patricia Belt ₃ , Laura Wilson ₃ , Naga P Chalasani ₉ , David E Kleiner ₁₄ ,

Affiliation

Cleveland Clinic, Cleveland, Ohio, USA.
Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Pacific Rim Pathology, San Diego, California, USA.
Saint Louis University, St. Louis, Missouri, USA.
University of California San Francisco, San Francisco, California, USA.
Duke University, Durham, North Carolina, USA.
University of Washington, Seattle, Washington, USA.
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Virginia Commonwealth University Health System, Richmond, Virginia, USA.
Duke Clinical Research Institute, Durham, North Carolina, USA.
University of California San Diego, San Diego, California, USA.
National Institute of Allergy and Infectious Disease (NIAID), Bethesda, Maryland, USA.
Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in people with HIV (PWH). The morphological spectrum of MASLD compared to matched controls and of the correlation between the NAFLD activity score (NAS) and fibrosis stage in PWH remains unknown.

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