The anthropologist Helen Fisher, who died just a few weeks ago, was well known for her many elegant studies on the pharmacology and neuroanatomy of the three primary emotions associated with mating and reproduction: sexual desire or lust, romantic love, and long term attachment or devotion. Lust, she thought, was mediated in the brain by oestrogens and androgens, romantic love by increases in dopaminergic and adrenergic function and reduced serotonergic function, largely in the right ventral tegmental area and the right caudate nucleus, and attachment by oxytocin and vasopressin, largely in the ventral pallidum. Drugs that might be thought to have aphrodisiac properties might be modelled on these findings, but beneficial effects have either not been confirmed or have not been impressive in clinical trials, and adverse effects are always a concern. The death recently of the anthropologist Helen Fisher reminds us, through her many elegant studies on the subject, of the pharmacological systems associated with love and sex. Fisher described three primary emotions associated with mating and reproduction: the sex drive or lust, romantic attraction or love, and attachment or devotion.12 Based largely on the results of published animal experiments, she initially connected each of these with pharmacological systems: sex drive with oestrogens and androgens; attraction with increased brain activity of dopamine and noradrenaline (norepinephrine) and reduced activity of 5-hydroxytyptamine (serotonin); and devotion with the neuropeptides vasopressin and oxytocin. These three different emotions can co-exist, …

中文翻译：

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当我用一个词的时候。 。 。爱与性的药理学


几周前去世的人类学家海伦·费舍尔 (Helen Fisher) 因其对与交配和繁殖相关的三种主要情绪的药理学和神经解剖学的许多优雅研究而闻名：性欲或欲望、浪漫的爱情以及长期依恋或依赖。奉献精神。她认为，性欲是通过大脑中的雌激素和雄激素介导的，浪漫的爱情是通过多巴胺能和肾上腺素能功能的增加以及血清素能功能的减少（主要在右腹侧被盖区和右侧尾状核）介导的，而依恋则主要是通过催产素和加压素介导的。在腹侧苍白球。可能被认为具有壮阳功效的药物可能会以这些发现为模型，但有益效果要么尚未得到证实，要么在临床试验中尚未令人印象深刻，而副作用始终是一个问题。人类学家海伦·费舍尔最近去世，通过她对这一主题的许多精彩研究，提醒我们与爱和性相关的药理学系统。费舍尔描述了与交配和繁殖相关的三种主要情绪：性欲或欲望、浪漫的吸引力或爱情，以及依恋或奉献。 12 主要基于已发表的动物实验结果，她最初将这些情绪与药理学系统联系起来：性欲与雌激素和雄激素；增加大脑中多巴胺和去甲肾上腺素（去甲肾上腺素）活性以及减少 5-羟色胺（血清素）活性的吸引力；以及神经肽加压素和催产素的奉献。这三种不同的情绪可以共存，...