Identification of mpox M1R and B6R monoclonal and bispecific antibodies that efficiently neutralize authentic mpox virus,Emerging Microbes & Infections

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Identification of mpox M1R and B6R monoclonal and bispecific antibodies that efficiently neutralize authentic mpox virus
Emerging Microbes & Infections ( IF 8.4 ) Pub Date : 2024-09-19 , DOI: 10.1080/22221751.2024.2401931
Zuning Ren _{1,

2} , Mengjun Li ₂ , Jiayin Chen ₂ , Xiaohua Gong ₃ , Shuo Song ₃ , Delin Li ₄ , Minghui Yang ₅ , Jianhai Yu ₂ , Sadia Asghar ₆ , Yanxin Cui ₃ , Shiyu Niu ₃ , Zhonghui Liao ₃ , Yushan Jiang ₂ , Jiahui Liu ₂ , Yuqing Li ₂ , Bao Zhang ₂ , Wei Zhao ₂ , Jie Peng ₁ , Yang Yang ₃ , Chenguang Shen _{2,

7}

Affiliation

State Key Laboratory of Organ Failure Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health; Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, People's Republic of China.
Laboratory of Protein Engineering and Vaccines, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.
School of Life Science, Advanced Research Institute of Multidisciplinary Science, Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, People's Republic of China.
Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.
Key Laboratory of Infectious Diseases Research in South China, Southern Medical University, Ministry of Education, People's Republic of China.

In 2022, the monkeypox virus (mpox virus, MPXV) exhibited global dissemination across six continents, representing a notable challenge owing to the scarcity of targeted antiviral interventions. Pas...

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