Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis
The Lancet ( IF 98.4 ) Pub Date : 2024-09-01 , DOI: 10.1016/s0140-6736(24)01733-1 Pardeep S Jhund 1 , Atefeh Talebi 1 , Alasdair D Henderson 1 , Brian L Claggett 2 , Muthiah Vaduganathan 2 , Akshay S Desai 2 , Carolyn S P Lam 3 , Bertram Pitt 4 , Michele Senni 5 , Sanjiv J Shah 6 , Adriaan A Voors 7 , Faiez Zannad 8 , Scott D Solomon 2 , John J V McMurray 1
The Lancet ( IF 98.4 ) Pub Date : 2024-09-01 , DOI: 10.1016/s0140-6736(24)01733-1 Pardeep S Jhund 1 , Atefeh Talebi 1 , Alasdair D Henderson 1 , Brian L Claggett 2 , Muthiah Vaduganathan 2 , Akshay S Desai 2 , Carolyn S P Lam 3 , Bertram Pitt 4 , Michele Senni 5 , Sanjiv J Shah 6 , Adriaan A Voors 7 , Faiez Zannad 8 , Scott D Solomon 2 , John J V McMurray 1
Affiliation
Mineralocorticoid receptor antagonists (MRAs) reduce hospitalisations and death in patients with heart failure and reduced ejection fraction (HFrEF), but the benefit in patients with heart failure and mildly reduced ejection fraction (HFmrEF) or heart failure and preserved ejection fraction (HFpEF) is unclear. We evaluated the effect of MRAs in four trials that enrolled patients with heart failure across the range of ejection fraction.
中文翻译:
盐皮质激素受体拮抗剂治疗心力衰竭:个体患者水平的荟萃分析
盐皮质激素受体拮抗剂 (MRA) 可减少射血分数降低 (HFrEF) 心力衰竭患者的住院和死亡,但对射血分数轻度降低 (HFmrEF) 或心力衰竭射血分数保留 (HFpEF) 患者的益处尚不清楚。我们在四项试验中评估了 MRA 的效果,这些试验招募了射血分数范围内的心力衰竭患者。
更新日期:2024-09-01
中文翻译:
盐皮质激素受体拮抗剂治疗心力衰竭:个体患者水平的荟萃分析
盐皮质激素受体拮抗剂 (MRA) 可减少射血分数降低 (HFrEF) 心力衰竭患者的住院和死亡,但对射血分数轻度降低 (HFmrEF) 或心力衰竭射血分数保留 (HFpEF) 患者的益处尚不清楚。我们在四项试验中评估了 MRA 的效果,这些试验招募了射血分数范围内的心力衰竭患者。