Circulating apoE4 protein levels from dried blood spots predict cognitive function in a large population-based survey setting,Alzheimer's & Dementia

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Circulating apoE4 protein levels from dried blood spots predict cognitive function in a large population-based survey setting
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-09-05 , DOI: 10.1002/alz.14224
Yacila I Deza-Lougovski _{1,

2} , Luzia M Weiss ₂ , Hannah M Horton _{2,

3} , Aijing Sun _{2,

3} , Nis Borbye-Lorenzen ₄ , Kristin Skogstrand ₄ , Solveig Holmgaard ₄ , Karen Andersen-Ranberg _{5,

6} , Vania Panes Lundmark _{7,

8} , Axel Börsch-Supan _{2,

3} , Martina Börsch-Supan _{3,

9} , Anna Rieckmann _{1,

2}

Affiliation

The apolipoprotein E (APOE) ε4 allele carries risk for cognitive impairment, but whether the level of circulating apoE4 protein in carriers affects cognition is unclear, as is how health and lifestyle impact circulating apoE4 levels.

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