Review article: Faecal biomarkers for assessing small intestinal damage in coeliac disease and environmental enteropathy,Alimentary Pharmacology & Therapeutics

当前位置： X-MOL 学术 › Aliment. Pharm. Ther. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Review article: Faecal biomarkers for assessing small intestinal damage in coeliac disease and environmental enteropathy
Alimentary Pharmacology & Therapeutics ( IF 6.6 ) Pub Date : 2024-09-05 , DOI: 10.1111/apt.18234
Laura Kivelä _{1,

2,

3,

4} , Katri Lindfors ₂ , Knut E A Lundin _{5,

6} , Ketil Størdal _{1,

7}

Affiliation

In coeliac disease and environmental enteropathy, dietary gluten and enteric infections cause reversible inflammation and morphological changes to the small intestinal mucosa that can be detected in biopsy samples obtained by endoscopy. However, there is a clear need for non-invasive biomarkers. Constant shedding of mucosal material into the bowel lumen and faeces, together with easy availability of stool, makes it an interesting sample matrix.

中文翻译：

综述文章：粪便生物标志物评估乳糜泻和环境性肠病中小肠损伤

在乳糜泻和环境性肠病中，膳食麸质和肠道感染会导致小肠粘膜的可逆性炎症和形态学变化，这可以在内镜检查获得的活检样本中检测到。然而，显然需要非侵入性生物标志物。粘膜物质不断脱落到肠腔和粪便中，再加上粪便容易获得，使其成为一种有趣的样本基质。

更新日期：2024-09-05

点击分享查看原文

点击收藏

公开下载

阅读更多本刊新发论文本刊介绍/投稿指南