In this issue of Molecular Cell, Sahu et al.¹ find that shielding heterochromatin from SWI/SNF chromatin remodelers is essential to maintain and epigenetically propagate pre-existing heterochromatin domains, whereas SWI/SNF action protects facultative heterochromatic regions from premature silencing.

中文翻译：

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异染色质：躲避重塑机器

在本期《分子细胞》中，Sahu 等人。 ¹发现，屏蔽异染色质免受 SWI/SNF 染色质重塑对于维持和表观遗传繁殖预先存在的异染色质结构域至关重要，而 SWI/SNF 作用可保护兼性异染色质区域免于过早沉默。