While the placenta regulates nutritional exchange between mother and fetus, Yu et al. reveal that human placental development is itself nutrient-sensitive. They elucidate entwined metabolic and epigenetic transitions driving syncytialization and pinpoint a requirement for the metabolite acetyl-CoA, which is sensitive to glucose metabolism.

中文翻译：

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乙酸解救：乙酰辅酶A促进胎盘发育


虽然胎盘调节母亲和胎儿之间的营养交换，Yu 等人。揭示人类胎盘发育本身对营养敏感。他们阐明了驱动合胞化的相互交织的代谢和表观遗传转变，并确定了对葡萄糖代谢敏感的代谢物乙酰辅酶A的需求。