Objective To elicit expert opinion and gain consensus on specific exercise intervention parameters to minimise hip bone mineral density (BMD) loss following traumatic lower limb amputation. Methods In three Delphi rounds, statements were presented to a panel of 13 experts from six countries. Experts were identified through publications or clinical expertise. Round 1 involved participants rating their agreement with 22 exercise prescription statements regarding BMD loss post amputation using a 5-point Likert scale. Agreement was deemed as 3–4 on the scale (agree/strongly agree). Statements of <50% agreement were excluded. Round 2 repeated remaining statements alongside round 1 feedback. Round 3 allowed reflection on round 2 responses considering group findings and the chance to change or maintain the resp onse. Round 3 statements reaching ≥70% agreement were defined as consensus. Results All 13 experts completed rounds 1, 2 and 3 (100% completion). Round 1 excluded 12 statements and added 1 statement (11 statements for rounds 2–3). Round 3 reached consensus on nine statements to guide future exercise interventions. Experts agreed that exercise interventions should be performed at least 2 days per week for a minimum of 6 months, including at least three different resistance exercises at an intensity of 8–12 repetitions. Interventions should include weight-bearing and multiplanar exercises, involve high-impact activities and be supervised initially. Conclusion This expert Delphi process achieved consensus on nine items related to exercise prescription to minimise hip BMD loss following traumatic lower limb amputation. These recommendations should be tested in future interventional trials. Data are available upon reasonable request.

中文翻译：

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开发运动干预以尽量减少创伤性下肢截肢后髋骨矿物质密度损失：Delphi 研究


目的 征求专家意见并就具体运动干预参数达成共识，以尽量减少创伤性下肢截肢后髋骨密度 （BMD） 损失。方法 在三轮 Delphi 中，向来自 6 个国家的 13 名专家组成的小组提交了声明。通过出版物或临床专业知识确定专家。第 1 轮涉及参与者使用 5 点李克特量表对他们对 22 项关于截肢后 BMD 损失的运动处方声明的同意程度进行评分。同意被视为量表上的 3-4（同意/非常同意）。<50% 一致性的陈述被排除在外。第 2 轮重复了剩余的陈述以及第 1 轮的反馈。第 3 轮允许对第 2 轮的回答进行反思，考虑小组调查结果以及更改或保持回复的机会。达到 ≥70% 同意的第 3 轮声明被定义为共识。结果：所有 13 名专家都完成了第 1、2 和 3 轮（100% 完成）。第 1 轮排除了 12 个语句，增加了 1 个语句（第 2-3 轮有 11 个语句）。第 3 轮就指导未来运动干预的 9 项声明达成共识。专家一致认为，运动干预应每周至少 2 天进行，至少持续 6 个月，包括至少三种不同的阻力练习，强度为 8-12 次重复。干预措施应包括负重和多平面锻炼，涉及高冲击力活动，并在最初接受监督。结论 该专家 Delphi 过程在与运动处方相关的 9 个项目上达成共识，以最大限度地减少创伤性下肢截肢后髋关节 BMD 损失。这些建议应在未来的干预试验中进行测试。数据可根据合理要求提供。