An integrated study on the levels of 7 polybrominated diphenyl ethers (PBDEs) in house dust and breast milk samples from women (N = 30) living in these households was conducted. ∑PBDEs ranged from <LOD to 523 ng g−1 dust (median 4.9 ng g−1 dust), and from 0.16 to 6.3 ng g−1 lipid weight (lw) (median 0.49 ng g−1 lw), in house dust and breast milk samples, respectively. Statistically significant correlations were observed between the mass fractions of BDE-153 from breast milk, and BDE-47, BDE-99 and BDE-100 from house dust, congeners that all originate from the “penta” formulation, indicating its dominance as PBDE exposure source in the examined household dusts. The number of electronic and electrical devices, and age of the building were positive, and the number of upholstered furniture and household area were negative predictors of PBDE dust levels. Mothers age was negative predictor of the PBDE levels in breast milk, possibly due to dilution of PBDEs in total body fat accumulated over the years. The results of health risk assessment suggest that detected PBDE levels don’t pose non-carcinogenic risk to the study population.

中文翻译：

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成对粉尘-母乳样品中的多溴二苯醚：水平、污染预测因子和婴儿和母亲的健康风险评估


对居住在这些家庭中的妇女 （N = 30） 的室内灰尘和母乳样本中 7 种多溴联苯醚 （PBDE） 的水平进行了综合研究。室内灰尘和母乳样品中，∑PBDE 的含量范围分别为 <LOD 至 523 ng g-1 粉尘（中位数 4.9 ng g-1 粉尘）和 0.16 至 6.3 ng g-1 脂质重 （lw）（中位数 0.49 ng g-1 lw）。在母乳中 BDE-153 的质量分数与室内灰尘中的 BDE-47、BDE-99 和 BDE-100 质量分数之间观察到统计学上的显著相关性，这些同系物均来自“penta”配方，表明其在所检查的家庭灰尘中作为 PBDE 暴露源占主导地位。电子和电气设备的数量和建筑物的年龄是正的，软垫家具的数量和家庭面积是多溴联苯醚粉尘水平的负预测指标。母亲年龄是母乳中 PBDE 水平的阴性预测因子，可能是由于多年来积累的全身脂肪中 PBDE 的稀释。健康风险评估的结果表明，检测到的 PBDE 水平不会对研究人群构成非致癌风险。