The Western Mediterranean coast is under the influence of anthropogenic pressures, including land use, increasing amounts of dangerous waste and habitat destruction. In 2021, the French RINBIO network (http://www.ifremer.fr/envlit/) originally dedicated to assess chemical contamination in the region, focused on biological effects produced by contaminants and the interaction with natural variability in mussels using an active caging strategy. Cell and tissue level biomarkers were applied for 17 sampling sites divided in three sub-regions categorized by different environmental conditions. Results provide critical information for ecosystem health assessment using mussels as sentinel species in the Western Mediterranean Sea. The influence of natural and confounding factors (trophic condition, reproductive cycle, caging strategy), on biological responses to mild chemical contamination, was discussed and discriminated for health status assessment. Results provide valuable data available as reference values for the assessment of biomarkers and histopathological alterations for large-scale active biomonitoring campaigns in the Western Mediterranean Sea.

中文翻译：

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用于西地中海健康状况评估的主动贻贝生物监测


地中海西海岸受到人为压力的影响，包括土地使用、危险废物数量增加和栖息地破坏。 2021 年，法国 RINBIO 网络 (http://www.ifremer.fr/envlit/) 最初致力于评估该地区的化学污染，重点关注污染物产生的生物效应以及使用主动笼养贻贝与自然变异的相互作用战略。细胞和组织水平生物标志物应用于按不同环境条件分为三个子区域的 17 个采样点。结果为利用贻贝作为西地中海哨兵物种的生态系统健康评估提供了关键信息。讨论并区分了自然因素和混杂因素（营养条件、繁殖周期、笼养策略）对轻度化学污染的生物反应的影响，以进行健康状况评估。结果提供了宝贵的数据，可作为评估西地中海大规模主动生物监测活动的生物标志物和组织病理学变化的参考值。