Aims Endoprosthetic reconstruction following distal femur tumour resection has been widely advocated. In this paper, we present the design of an uncemented endoprosthesis system featuring a short, curved stem, with the goal of enhancing long-term survivorship and functional outcomes. Methods This study involved patients who underwent implantation of an uncemented distal femoral endoprosthesis with a short and curved stem between 2014 and 2019. Functional outcomes were assessed using the 1993 version of the Musculoskeletal Tumour Society (MSTS-93) score. Additionally, we quantified five types of complications and assessed osseointegration radiologically. The survivorship of the endoprosthesis was evaluated according to two endpoints. A total of 134 patients with a median age of 26 years (IQR 16 to 41) were included in our study. The median follow-up time was 61 months (IQR 56 to 76), and the median functional MSTS-93 was 83% (IQR 73 to 91) postoperatively. Results Overall, 21 patients (16%) encountered complications, and the rate of aseptic loosening was 7% (9/134). The survival rate up to 8.5 years was 93% for aseptic loosening as the endpoint, and 88% for any reason as the endpoint, retrospectively. Conclusion The use of an uncemented distal femoral endoprosthesis with a short, curved stem demonstrated a low incidence of aseptic loosening and achieved long-term survivorship of up to nine years. Meanwhile, aseptic loosening typically occurs in the early stage postoperatively.

中文翻译：

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骨肿瘤患者具有短弯曲柄的非骨水泥远端股骨内置假体的生存率、并发症和功能结果。


目的 股骨远端肿瘤切除术后的内假体重建已被广泛提倡。在本文中，我们提出了一种非骨水泥内置假体系统的设计，该系统具有短而弯曲的柄，其目标是提高长期生存率和功能结果。方法 本研究涉及 2014 年至 2019 年间接受植入短而弯曲柄的非骨水泥远端股骨内置假体的患者。使用 1993 年版肌肉骨骼肿瘤协会 (MSTS-93) 评分评估功能结果。此外，我们还量化了五种类型的并发症，并通过放射学评估了骨整合。根据两个终点评估内置假体的存活率。我们的研究共纳入了 134 名中位年龄为 26 岁（IQR 16 至 41）的患者。中位随访时间为 61 个月（IQR 56 至 76），术后中位功能 MSTS-93 为 83%（IQR 73 至 91）。结果 总体而言，21 名患者（16%）出现并发症，无菌性松动率为 7%（9/134）。回顾性分析，以无菌性松动为终点的 8.5 年生存率为 93%，以任何原因为终点的生存率为 88%。结论 使用带有短弯曲柄的非骨水泥远端股骨内置假体，无菌性松动的发生率较低，并实现了长达九年的长期生存。同时，无菌性松动通常发生在术后早期。