Reliability of Intestinal Ultrasound for Evaluating Crohn’s Disease Activity Using Point-of-care and Central Reading,Clinical Gastroenterology and Hepatology

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Reliability of Intestinal Ultrasound for Evaluating Crohn’s Disease Activity Using Point-of-care and Central Reading
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-08-28 , DOI: 10.1016/j.cgh.2024.08.007
Thomas M Goodsall ₁ , Yoon-Kyo An ₂ , Jane M Andrews ₃ , Jakob Begun ₂ , Antony B Friedman ₄ , Andrew Lee ₅ , Peter J Lewindon ₆ , Paul Spizzo ₇ , Nick Rodgers ₈ , Kirstin M Taylor ₄ , Lauren S White ₉ , Rune Wilkens ₁₀ , Emily K Wright ₁₁ , Lily Zou ₁₂ , Bryan R Maguire ₁₂ , Claire E Parker ₁₂ , Julie Rémillard ₁₂ , Kerri L Novak ₁₃ , Remo Panaccione ₁₃ , Brian G Feagan ₁₄ , Vipul Jairath ₁₄ , Christopher Ma ₁₅ , Robert V Bryant ₁

Affiliation

IBD Service, Department of Gastroenterology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia; Faculty of Health Sciences, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Mater Hospital Brisbane, University of Queensland, Brisbane, Queensland, Australia; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.
Faculty of Health Sciences, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia; Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Victoria, Australia.
Department of Gastroenterology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Department of Gastroenterology, Queensland Children's Hospital, University of Queensland, Brisbane, Queensland, Australia.
Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre, Bedford Park, South Australia, Australia.
Clinpath Pathology Laboratory, Adelaide, South Australia, Australia.
Sunshine Coast University Hospital, Birtinya, Queensland, Australia.
Digestive Disease Centre, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark; Copenhagen Intestinal Ultrasound (CIUS), Copenhagen, Denmark.
Department of Gastroenterology, St Vincent's Hospital, University of Melbourne, Melbourne, Victoria, Australia.
Alimentiv Inc., London, Ontario, Canada.
Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Alimentiv Inc., London, Ontario, Canada; Division of Gastroenterology, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Division of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Copenhagen Intestinal Ultrasound (CIUS), Copenhagen, Denmark; Alimentiv Inc., London, Ontario, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.

Intestinal ultrasound (IUS) is increasingly used to assess Crohn’s disease (CD) activity in clinical practice. However, application in clinical trials has been limited by heterogeneous scoring methods and concerns about reliability. We aimed to determine the inter- and intra-rater reliability of locally and centrally read IUS parameters for evaluating CD using prospectively performed scans.

中文翻译：

肠道超声使用床旁和中央读数评估克罗恩病活动的可靠性

肠道超声（IUS）在临床实践中越来越多地用于评估克罗恩病（CD）活动。然而，由于评分方法的异质性和对可靠性的担忧，临床试验中的应用受到限制。我们旨在确定本地和集中读取的 IUS 参数的评分者间和评分者内可靠性，以使用前瞻性扫描来评估 CD。

更新日期：2024-08-28

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