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Distinctive small molecules blend: Promotes lacrimal gland epithelial cell proliferation in vitro and accelerates lacrimal gland injury repair in vivo
The Ocular Surface ( IF 5.9 ) Pub Date : 2024-08-28 , DOI: 10.1016/j.jtos.2024.08.014 Baihui Zeng 1 , Lina Xu 2 , Guoliang Wang 2 , Ruize Shi 1 , Kerui Wang 3 , Shurong Wang 1 , Cheng Li 4
The Ocular Surface ( IF 5.9 ) Pub Date : 2024-08-28 , DOI: 10.1016/j.jtos.2024.08.014 Baihui Zeng 1 , Lina Xu 2 , Guoliang Wang 2 , Ruize Shi 1 , Kerui Wang 3 , Shurong Wang 1 , Cheng Li 4
Affiliation
This study aims to develop a novel serum-free culture strategy containing only two small molecules, Y27632 and SB431542 (2C), for in vitro expansion of mouse lacrimal gland epithelial cells (LGECs) and investigate an innovative therapeutic approach for lacrimal gland (LG) injury.
中文翻译:
独特的小分子混合物:在体外促进泪腺上皮细胞增殖,在体内加速泪腺损伤修复
本研究旨在开发一种新型无血清培养策略,仅包含 Y27632 和 SB431542 (2C) 两个小分子,用于小鼠泪腺上皮细胞 (LGECs) 的体外扩增,并研究一种针对泪腺 (LG) 损伤的创新治疗方法。
更新日期:2024-08-28
中文翻译:
独特的小分子混合物:在体外促进泪腺上皮细胞增殖,在体内加速泪腺损伤修复
本研究旨在开发一种新型无血清培养策略,仅包含 Y27632 和 SB431542 (2C) 两个小分子,用于小鼠泪腺上皮细胞 (LGECs) 的体外扩增,并研究一种针对泪腺 (LG) 损伤的创新治疗方法。