Drug overdose deaths remain a public health crisis in the United States; nearly 107,000 and nearly 108,000 deaths occurred in 2021 and 2022, respectively. Persons with mental health conditions are at increased risk for overdose. In addition, substance use disorders and non-substance-related mental health disorders (MHDs) frequently co-occur. Using data from CDC's State Unintentional Drug Overdose Reporting System, this report describes characteristics of persons in 43 states and the District of Columbia who died of unintentional or undetermined intent drug overdose and had any MHD. In 2022, 21.9% of persons who died of drug overdose had a reported MHD. Using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria, the most frequently reported MHDs were depressive (12.9%), anxiety (9.4%), and bipolar (5.9%) disorders. Overall, approximately 80% of overdose deaths involved opioids, primarily illegally manufactured fentanyls. Higher proportions of deaths among decedents with an MHD involved antidepressants (9.7%) and benzodiazepines (15.3%) compared with those without an MHD (3.3% and 8.5%, respectively). Nearly one quarter of decedents with an MHD had at least one recent potential opportunity for intervention (e.g., approximately one in 10 decedents were undergoing substance use disorder treatment, and one in 10 visited an emergency department or urgent care facility within 1 month of death). Expanding efforts to identify and address co-occurring mental health and substance use disorders (e.g., integrated screening and treatment) and strengthen treatment retention and harm reduction services could save lives.

中文翻译：

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因药物过量死亡者报告的非物质相关心理健康障碍 - 美国，2022 年。


药物过量死亡仍然是美国的公共卫生危机； 2021 年和 2022 年分别有近 107,000 人和近 108,000 人死亡。有精神健康问题的人服药过量的风险增加。此外，物质使用障碍和非物质相关的精神健康障碍 (MHD) 经常同时发生。本报告使用 CDC 州无意药物过量报告系统的数据，描述了 43 个州和哥伦比亚特区因无意或未确定意图的药物过量而死亡并患有任何 MHD 的人员的特征。 2022 年，因药物过量死亡的人中有 21.9% 患有 MHD。根据《精神疾病诊断和统计手册》第五版标准，最常报告的 MHD 是抑郁症 (12.9%)、焦虑症 (9.4%) 和双相情感障碍 (5.9%)。总体而言，大约 80% 的过量死亡涉及阿片类药物，主要是非法制造的芬太尼。与没有 MHD 的死者（分别为 3.3% 和 8.5%）相比，患有 MHD 的死者中涉及抗抑郁药（9.7%）和苯二氮卓类药物（15.3%）的死亡比例更高。近四分之一的患有 MHD 的死者最近至少有一次潜在的干预机会（例如，大约十分之一的死者正在接受药物滥用障碍治疗，十分之一的死者在死亡后 1 个月内去过急诊室或紧急护理机构） 。加大力度识别和解决同时发生的精神健康和药物滥用障碍（例如综合筛查和治疗）并加强治疗保留和减少伤害服务可以挽救生命。