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Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients With Crohn's Disease-Like Pouch Inflammation.
The American Journal of Gastroenterology ( IF 8.0 ) Pub Date : 2024-08-27 , DOI: 10.14309/ajg.0000000000003055 Maia Kayal 1 , Hannah Posner , Darwin Jimenez , Justin Huang , Marla C Dubinsky , Jean Frederic Colombel
The American Journal of Gastroenterology ( IF 8.0 ) Pub Date : 2024-08-27 , DOI: 10.14309/ajg.0000000000003055 Maia Kayal 1 , Hannah Posner , Darwin Jimenez , Justin Huang , Marla C Dubinsky , Jean Frederic Colombel
Affiliation
INTRODUCTION
The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy.
METHODS
This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy.
RESULTS
Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response.
DISCUSSION
Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.
中文翻译:
内窥镜反应可降低克罗恩病样贮袋炎症患者继发贮袋炎的风险。
引言 本研究的目的是报告内窥镜反应和缓解的频率和缓解对治疗中克罗恩病样贮袋炎 (CDLPI) 患者后续贮袋炎风险的影响。方法 这是一项针对 18 岁以上接受治疗的 CDLPI 患者的单中心回顾性研究。结果 在 110 例临床缓解的 CDLPI 患者中,与内窥镜反应相比,内窥镜缓解与后续贮袋炎风险降低无显著相关性。讨论 内窥镜反应,而不是缓解,足以降低 CDLPI 患者后续贮袋炎的风险。
更新日期:2024-08-27
中文翻译:
内窥镜反应可降低克罗恩病样贮袋炎症患者继发贮袋炎的风险。
引言 本研究的目的是报告内窥镜反应和缓解的频率和缓解对治疗中克罗恩病样贮袋炎 (CDLPI) 患者后续贮袋炎风险的影响。方法 这是一项针对 18 岁以上接受治疗的 CDLPI 患者的单中心回顾性研究。结果 在 110 例临床缓解的 CDLPI 患者中,与内窥镜反应相比,内窥镜缓解与后续贮袋炎风险降低无显著相关性。讨论 内窥镜反应,而不是缓解,足以降低 CDLPI 患者后续贮袋炎的风险。