While innumerous associative microbiome studies have been published, mechanistic links between the microbiome and host physiology remain much scarcer. In Cell Host & Microbe, Shen et al. report the effect of soluble dietary fibers in alcohol-related liver disease. Through microbiome remodeling, dietary fiber triggers upregulation of liver ornithine aminotransferase and a subsequent reduction in hepatic damage.

中文翻译：

---

酸性拟杆菌：将膳食纤维与肝脏健康联系起来

尽管已经发表了大量相关微生物组研究，但微生物组和宿主生理学之间的机制联系仍然很少。在《细胞宿主与微生物》中，Shen 等人。报告可溶性膳食纤维对酒精相关肝病的影响。通过微生物组重塑，膳食纤维可引发肝脏鸟氨酸转氨酶的上调，从而减少肝损伤。