Wearable health monitoring platforms require advanced sensing modalities with integrated electronics. However, current systems suffer from limitations related to energy supply, sensing capabilities, circuitry regulations and large form factors. Here, we report an autonomous and continuous sweat sensing system that operates on a fingertip. The system uses a self-voltage-regulated wearable microgrid based on enzymatic biofuel cells and AgCl-Zn batteries to harvest and store bioenergy from sweat, respectively. It relies on osmosis to continuously supply sweat to the sensor array for on-demand multi-metabolite sensing and is combined with low-power electronics for signal acquisition and wireless data transmission. The wearable system is powered solely by fingertip perspiration and can detect glucose, vitamin C, lactate and levodopa over extended periods of time.

可穿戴健康监测平台需要具有集成电子设备的先进传感方式。然而，当前的系统受到与能源供应、传感能力、电路调节和大尺寸相关的限制。在这里，我们报告了一种在指尖上运行的自主连续汗液传感系统。该系统使用基于酶生物燃料电池和AgCl-Zn电池的自电压调节可穿戴微电网，分别从汗液中收集和存储生物能。它依靠渗透作用持续向传感器阵列提供汗液，以实现按需的多代谢物传感，并与低功耗电子器件相结合，用于信号采集和无线数据传输。该可穿戴系统仅由指尖汗液供电，可以长时间检测葡萄糖、维生素 C、乳酸和左旋多巴。