Autoimmune diseases such as systemic lupus erythematosus preferentially affect women, and multiple hypotheses are under investigation to elucidate this phenomenon. Emerging research suggests that multiple pathophysiological mechanisms and pathways are likely involved, including several that involve the X chromosome, but is skewing of X chromosome inactivation one of them?

中文翻译：

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X 染色体失活是 SLE 的原因还是影响？


系统性红斑狼疮等自身免疫性疾病优先影响女性，目前正在研究多种假设来阐明这一现象。新兴研究表明，可能涉及多种病理生理机制和途径，其中包括一些涉及 X 染色体的机制和途径，但 X 染色体失活的倾斜是其中之一吗？