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Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-09-01 , DOI: 10.1002/alz.14207
Matthew D Howe 1, 2 , Megan R Caruso 1 , Masood Manoochehri 1 , Zachary J Kunicki 2 , Sheina Emrani 3 , James L Rudolph 4, 5 , Edward D Huey 1, 2 , Stephen P Salloway 1, 2 , Hwamee Oh 2 ,
Affiliation  

The relationship between cerebrovascular disease (CVD) and amyloid beta (Aβ) in Alzheimer's disease (AD) is understudied. We hypothesized that magnetic resonance imaging (MRI)–based CVD biomarkers—including cerebral microbleeds (CMBs), lacunar infarction, and white matter hyperintensities (WMHs)—would correlate with Aβ positivity on positron emission tomography (Aβ-PET).

中文翻译:


脑血管成像生物标志物检测脑淀粉样变性的应用



阿尔茨海默病 (AD) 中脑血管疾病 (CVD) 和淀粉样蛋白 β (Aβ) 之间的关系研究不足。我们假设基于磁共振成像 (MRI) 的 CVD 生物标志物——包括脑微出血 (CMB) 、腔隙性梗死和白质高信号 (WMH)——与正电子发射断层扫描 (Aβ-PET) 上的 Aβ 阳性相关。
更新日期:2024-09-01
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