Synergistic associations of CD33 variants and hypertension with brain and cognitive aging among dementia-free older adults: A population-based study,Alzheimer's & Dementia

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Synergistic associations of CD33 variants and hypertension with brain and cognitive aging among dementia-free older adults: A population-based study
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-08-30 , DOI: 10.1002/alz.14209
Min Zhu _{1,

2,

3} , Xunyao Tian _{2,

3} , Xiaodong Han ₄ , Yixun Ma _{1,

3} , Wenxin Fa _{1,

3} , Nan Wang _{2,

3} , Rui Liu _{1,

2,

3} , Yi Dong _{1,

2,

3} , Yifei Ren _{2,

3} , Cuicui Liu _{1,

2,

3} , Na Tian _{1,

2,

3} , Heng Zhang _{1,

2,

3} , Lin Song _{1,

2,

3} , Shi Tang _{1,

2,

3} , Lin Cong _{1,

2,

3} , Yongxiang Wang _{1,

2,

3,

5,

6} , Tingting Hou _{1,

2,

3} , Chengxuan Qiu _{1,

5,

6} , Yifeng Du _{1,

2,

3,

5} ,

Affiliation

CD33 rs3865444 and hypertension (HTN) are related to cognitive impairment, individually. However, little is known about their combined effects on cognitive function in older adults.

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