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Mitochondrial transplants to treat mitochondrial dysfunction
Nature Metabolism ( IF 18.9 ) Pub Date : 2024-09-02 , DOI: 10.1038/s42255-024-01124-6 Alessandro Bitto 1
Nature Metabolism ( IF 18.9 ) Pub Date : 2024-09-02 , DOI: 10.1038/s42255-024-01124-6 Alessandro Bitto 1
Affiliation
A new approach to treating mitochondrial disorders is based on the transplantation of healthy mitochondria, and improves symptoms and survival in a mouse model of Leigh syndrome — a paediatric mitochondrial disease that is characterized by failure to thrive, lactic acidosis, and progressive degeneration.
中文翻译:
线粒体移植治疗线粒体功能障碍
一种治疗线粒体疾病的新方法基于健康线粒体的移植,并改善了 Leigh 综合征小鼠模型的症状和存活率——Leigh 综合征是一种以生长迟缓、乳酸性酸中毒和进行性变性为特征的儿科线粒体疾病。
更新日期:2024-09-02
中文翻译:
线粒体移植治疗线粒体功能障碍
一种治疗线粒体疾病的新方法基于健康线粒体的移植,并改善了 Leigh 综合征小鼠模型的症状和存活率——Leigh 综合征是一种以生长迟缓、乳酸性酸中毒和进行性变性为特征的儿科线粒体疾病。