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Intergenerational metabolism-disrupting effects of maternal exposure to plasticizer acetyl tributyl citrate (ATBC)
Environment International ( IF 10.3 ) Pub Date : 2024-08-20 , DOI: 10.1016/j.envint.2024.108967
Danyang Zhang 1 , Weigao Zhang 1 , Hu Liu 1 , Shuxian Huang 1 , Wangchao Huang 2 , Yunfeng Zhu 1 , Xuening Ma 1 , Yugui Xia 3 , Jianfa Zhang 1 , Wei Lu 4 , Da Shao 5 , Dan Weng 1
Affiliation  

Environmental chemicals and pollutants are increasingly recognized for their potential transgenerational effects. Acetyl tributyl citrate (ATBC), a widely used plasticizer substituting di-(2-ethylhexyl) phthalate (DEHP), was identified as an inducer of lipogenesis in male mice by our previous research. This study aimed to investigate the impact of ATBC exposure on the metabolic homeostasis of female mice and simultaneously evaluate its intergenerational effects.

中文翻译:


母亲接触增塑剂乙酰柠檬酸三丁酯(ATBC)对代际代谢的干扰作用



人们越来越认识到环境化学品和污染物具有潜在的跨代影响。柠檬酸乙酰三丁酯 (ATBC) 是一种广泛使用的增塑剂,可替代邻苯二甲酸二(2-乙基己基)酯 (DEHP),我们之前的研究发现它是雄性小鼠脂肪生成的诱导剂。本研究旨在探讨ATBC暴露对雌性小鼠代谢稳态的影响,并同时评估其代际效应。
更新日期:2024-08-20
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