Cell surface enzymes are important proteins that play essential roles in controlling a wide variety of biological processes, such as cell-cell adhesion, recognition and communication. Dysregulation of enzyme-catalyzed processes is known to contribute to numerous diseases, including cancer, cardiovascular diseases and neurodegenerative disease. From the perspective of drug discovery and development, there is a growing interest in detecting the cell surface enzyme activity, propelled by the arising need for innovative diagnostic and therapeutic approaches to address various health conditions.

中文翻译：

---

解锁细胞表面酶：检测酶活性的化学策略综述


细胞表面酶是重要的蛋白质，在控制各种生物过程（如细胞间粘附、识别和通讯）中起着至关重要的作用。众所周知，酶催化过程的失调会导致许多疾病，包括癌症、心血管疾病和神经退行性疾病。从药物发现和开发的角度来看，人们对检测细胞表面酶活性的兴趣日益浓厚，这是由于对解决各种健康状况的创新诊断和治疗方法的需求不断增长。