New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer,Journal of Advanced Research

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New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-08-24 , DOI: 10.1016/j.jare.2024.08.029
Lin Xu ₁ , Wanli Ma ₂ , Xiaoyu Huo ₂ , Jiao Luo ₂ , Ruoxi Li ₂ , Xiaoxiao Zhu ₂ , Xiangbin Kong ₂ , Kunming Zhao ₂ , Yuan Jin ₂ , Meihua Zhang ₃ , Xianshu Li ₃ , Ling Wang ₄ , Wei Han ₅ , Dianke Yu ₂

Affiliation

Extensive studies have established the correlation between long-term PM2.5 exposure and lung cancer, yet the mechanisms underlying this association remain poorly understood. PIWI-interacting RNAs (piRNAs), a novel category of small non-coding RNAs, serve important roles in various diseases. However, their biological function and mechanism in PM2.5-induced lung cancer have not been thoroughly investigated.

中文翻译：

piRNA PMLCPIR 促进 PM2.5 诱导的肺癌的功能和机制的新见解

广泛的研究已经确定了长期 PM2.5 暴露与肺癌之间的相关性，但这种关联的机制仍然知之甚少。PIWI 相互作用 RNA （piRNA）是一类新型小非编码 RNA，在各种疾病中起着重要作用。然而，它们在 PM2.5 诱导的肺癌中的生物学功能和机制尚未得到彻底研究。

更新日期：2024-08-24

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