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Clinical Application of Phage Immunoprecipitation Sequencing to Diagnose Enterovirus D68 as the Underlying Etiology in a Case of Guillain-Barré Syndrome
The Journal of Infectious Diseases ( IF 5.0 ) Pub Date : 2024-08-31 , DOI: 10.1093/infdis/jiae411 Fang Fang Li 1 , Alison Faber 2, 3 , Jessica M Caleta 4 , David M Goldfarb 1, 5, 6 , Inna Sekirov 1, 4 , Natalie A Prystajecky 1, 4 , Jocelyn A Srigley 1, 5, 6 , Ram Mishaal 2, 3, 6 , Agatha N Jassem 1, 4
The Journal of Infectious Diseases ( IF 5.0 ) Pub Date : 2024-08-31 , DOI: 10.1093/infdis/jiae411 Fang Fang Li 1 , Alison Faber 2, 3 , Jessica M Caleta 4 , David M Goldfarb 1, 5, 6 , Inna Sekirov 1, 4 , Natalie A Prystajecky 1, 4 , Jocelyn A Srigley 1, 5, 6 , Ram Mishaal 2, 3, 6 , Agatha N Jassem 1, 4
Affiliation
Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected cerebrospinal fluid antibodies against enterovirus D to link GBS with prior enterovirus D68 respiratory infection.
中文翻译:
噬菌体免疫沉淀测序诊断肠道病毒 D68 为格林-巴利综合征患者基础病因的临床应用
吉兰-巴雷综合征 (GBS) 是一种急性周围神经病变,通常先于呼吸道或胃肠道感染,但脑脊液的分子检测通常不确定。在加拿大不列颠哥伦比亚省最近一例严重的儿科 GBS 病例中,我们检测到针对肠道病毒 D 的脑脊液抗体,将 GBS 与既往肠道病毒 D68 呼吸道感染联系起来。
更新日期:2024-08-31
中文翻译:
噬菌体免疫沉淀测序诊断肠道病毒 D68 为格林-巴利综合征患者基础病因的临床应用
吉兰-巴雷综合征 (GBS) 是一种急性周围神经病变,通常先于呼吸道或胃肠道感染,但脑脊液的分子检测通常不确定。在加拿大不列颠哥伦比亚省最近一例严重的儿科 GBS 病例中,我们检测到针对肠道病毒 D 的脑脊液抗体,将 GBS 与既往肠道病毒 D68 呼吸道感染联系起来。