Sarcopenia is an age-related muscle disease that increases the risk of falls, disabilities, and death. It is associated with increased muscle protein degradation driven by molecular signalling pathways including Akt and FOXO1. This study aims to identify genes, gene interactions, and molecular pathways and processes associated with muscle aging and exercise in older adults that remained undiscovered until now leveraging on an artificial intelligence approach called artificial neural network inference (ANNi).

中文翻译：

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人工神经网络推理分析确定了与骨骼肌衰老相关的新基因和基因相互作用


肌肉减少症是一种与年龄相关的肌肉疾病，会增加跌倒、残疾和死亡的风险。它与 Akt 和 FOXO1 等分子信号通路驱动的肌肉蛋白降解增加有关。这项研究旨在利用一种称为人工神经网络推理 (ANNi) 的人工智能方法，识别与老年人肌肉衰老和运动相关的基因、基因相互作用以及分子途径和过程，这些过程和过程迄今为止尚未被发现。