Viscosity measurement is crucial in biomedical research and clinical diagnosis. Currently, rapid and non-contact methods for measuring viscosity remain challenging. We propose a method based on optical coherence tomography for fast, remote assessment of the liquid viscosity. The viscosity of the liquid sample was quantified according to Poiseuille's law, the flow velocity was determined using optical coherence tomography, and the real-time pressure difference was measured by two manometers. Glycerol–water mixtures with various viscosities were tested to assess the accuracy of the optical coherence tomography (OCT) viscosity measurement. Then, blood samples with different levels of hemodilution and hematocrit were measured to validate the feasibility of the OCT method in the blood viscosity measurement. The results indicate that the proposed method can provide rapid, non-contact liquid viscosity measurement. It could significantly impact research on hemodynamics and diagnosis of blood disorders.

中文翻译：

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基于光学相干层析成像的快速非接触式粘度测量


粘度测量在生物医学研究和临床诊断中至关重要。目前，用于测量粘度的快速和非接触式方法仍然具有挑战性。我们提出了一种基于光学相干断层扫描的方法，用于快速、远程评估液体粘度。根据泊肃叶定律量化液体样品的粘度，使用光学相干断层扫描确定流速，并通过两个压力计测量实时压力差。测试了不同粘度的甘油-水混合物，以评估光学相干断层扫描 （OCT） 粘度测量的准确性。然后，测量不同血液稀释度和血细胞比容水平的血样，以验证 OCT 方法在血液粘度测量中的可行性。结果表明，所提方法可以提供快速、非接触式的液体粘度测量。它可以显着影响血流动力学和血液疾病诊断的研究。