Antibiotics are among the most widely used pharmaceutically active compounds. Possessing the capability to adversely impact the ecological system, existence of antibiotics in the environment is an escalating concern. With the purpose of removing two widely used antibiotics efficiently from aqueous solutions, the competency of two biochar (BC)-based sorbents derived from spent coffee (SC) grounds was investigated. Both pristine (SCBC) and nickel (II) oxide-impregnated (Ni-SCBC) biochars were utilized as sustainable and cost-effective sorbents to remove daunorubicin (DAYN) and tigecycline (TIGY) from single synthetic aqueous solutions and binary combinations. Batch adsorption experiments were controlled implementing Box–Behnken design. The removal efficiency of Ni-SCBC was superior compared to SCBC (TIGY: 67.06%, DAYN: 94.30%). Results of characterizations showed that impregnation with NiO changed the degree of crystallization with a remarkable increase in the surface area from 49.23 m²/g in SCBC to 86.06 m²/g in Ni-SCBC. Adsorption of DAYN and TIGY (single solutions) conformed well to Freundlich, and Langmuir isotherms, respectively. A maximum adsorption capacity (q_max) of 136.62 mg/g (DAYN) and 73.15 mg/g (TIGY) was reported in single solutions, compared to 23.50 mg/g (DAYN) and 58.42 mg/g (TIGY) in binary mixture. Adsorption kinetics onto Ni-SCBC fitted well with the pseudo-second-order (PSO) and Elovich models. Acquired results demonstrated that SCBC and Ni-SCBC are promising adsorbents for remedying antibiotics.

抗生素是最广泛使用的药物活性化合物之一。环境中抗生素的存在会对生态系统产生不利影响，因此引起了越来越多的关注。为了从水溶液中有效去除两种广泛使用的抗生素，研究了两种源自废咖啡（SC）渣的生物炭（BC）吸附剂的能力。原始 (SCBC) 和氧化镍 (II) 浸渍 (Ni-SCBC) 生物炭都被用作可持续且经济高效的吸附剂，用于从单一合成水溶液和二元组合中去除柔红霉素 (DAYN) 和替加环素 (TIGY)。批量吸附实验通过 Box-Behnken 设计进行控制。 Ni-SCBC 的去除效率优于 SCBC（TIGY：67.06％，DAYN：94.30％）。表征结果表明，NiO 浸渍改变了结晶度，表面积显着增加，从 SCBC 中的 49.23 m ² /g 增加到 Ni-SCBC 中的 86.06 m ² /g。 DAYN 和 TIGY（单一溶液）的吸附分别很好地符合 Freundlich 和 Langmuir 等温线。单一溶液中的最大吸附容量 ( q _max ) 为 136.62 mg/g (DAYN) 和 73.15 mg/g (TIGY)，而二元混合物中的最大吸附容量 ( q max ) 为 23.50 mg/g (DAYN) 和 58.42 mg/g (TIGY) 。 Ni-SCBC 上的吸附动力学与伪二阶 (PSO) 和 Elovich 模型非常吻合。获得的结果表明，SCBC 和 Ni-SCBC 是有前途的抗生素治疗吸附剂。