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Quest for a genetic biomarker for sickle cell disease priapism: rationale, progress and implications
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2024-08-27 , DOI: 10.1038/s41585-024-00927-2
Oluwafolajimi Adesanya 1 , Arthur L Burnett 1
Affiliation  

Currently, no consensus biomarker exists for predicting priapism associated with sickle cell disease. Biochemical and haematological parameters have been investigated, but they are limited by a lack of specificity and the need for pre-validated thresholds. Genetic biomarkers are a potential alternative for further consideration in future efforts.

中文翻译:


寻找镰状细胞病阴茎异常勃起的遗传生物标志物:基本原理、进展和影响



目前,尚无一致的生物标志物可用于预测与镰状细胞病相关的阴茎异常勃起。已经对生化和血液学参数进行了研究,但由于缺乏特异性和需要预先验证阈值而受到限制。遗传生物标志物是未来工作中进一步考虑的潜在替代方案。
更新日期:2024-08-27
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