Toxicity of water accommodated fractions (WAF) from the oil spilled on the Brazilian coast at different stages of weathering were investigated using Danio rerio. Weathering stages included emulsified oil that reached the coast (OM) and oil collected 50 days later deposited on beach sand (OS) or adhered to shore rocks (OR). Parent and alkylated naphthalenes decreased whereas phenanthrenes increased from less weathered WAF-OM to more weathered WAF-OS and WAF-OR. More weathered WAF-OS and WAF-OR were more potent inducers of zebrafish developmental delay, suggesting that parent and alkylated phenanthrenes are involved. However, less weathered WAF-OM was a more potent inducer of failure in swim-bladder inflation than more weathered WAF-OS and WAF-OR, suggesting that parent and alkylated naphthalenes are involved. Decreases in heart rates and increased heart and skeletal deformities were observed in exposed larvae. Lowest observed effect concentrations for different developmental toxicity endpoints are within environmentally relevant polycyclic aromatic hydrocarbon concentrations.

中文翻译：

---

巴西海岸泄漏石油在不同程度的自然风化下对斑马鱼斑马鱼早期生命阶段的毒性


使用斑马鱼研究了巴西海岸溢油不同风化阶段的水容纳部分 (WAF) 的毒性。风化阶段包括到达海岸的乳化油 (OM) 和 50 天后收集的油沉积在海滩沙子 (OS) 或粘附在海岸岩石 (OR) 上。从风化程度较低的 WAF-OM 到风化程度较高的 WAF-OS 和 WAF-OR，母体萘和烷基化萘减少，而菲增加。风化程度更高的 WAF-OS 和 WAF-OR 是斑马鱼发育迟缓更有效的诱导剂，表明亲本菲和烷基化菲参与其中。然而，与风化程度较高的 WAF-OS 和 WAF-OR 相比，风化程度较低的 WAF-OM 是更有效的鱼鳔膨胀失败诱导剂，这表明母体萘和烷基化萘参与其中。在暴露的幼虫中观察到心率下降以及心脏和骨骼畸形增加。不同发育毒性终点的最低观察到的效应浓度在环境相关的多环芳烃浓度范围内。