There is a lack of research examining the interplay between objectively measured physical activity volume and intensity with life expectancy. Individuals from UK Biobank with wrist-worn accelerometer data were included. The average acceleration and intensity gradient were extracted to describe the physical activity volume and intensity profile. Mortality data were obtained from national registries. Adjusted life expectancies were estimated using parametric flexible survival models. 40,953 (57.1%) women (median age = 61.9 years) and 30,820 (42.9%) men (63.1 years) were included. Over a median follow-up of 6.9 years, there were 1719 (2.4%) deaths (733 in women; 986 in men). At 60 years, life expectancy was progressively longer for higher physical activity volume and intensity profiles, reaching 95.6 years in women and 94.5 years in men at the 90th centile for both volume and intensity, corresponding to 3.4 (95% confidence interval (95%CI): 2.4–4.4) additional years in women and 4.6 (95%CI: 3.6–5.6) additional years in men compared to those at the 10th centiles. An additional 10-min or 30-min daily brisk walk was associated with 0.9 (95%CI: 0.5–1.3) and 1.4 (95%CI: 0.9–1.9) years longer life expectancy, respectively, in inactive women; and 1.4 (95%CI: 1.0–1.8) and 2.5 (95%CI: 1.9–3.1) years in inactive men. Higher physical activity volumes were associated with longer life expectancy, with a higher physical activity intensity profile further adding to a longer life. Adding as little as a 10-min brisk walk to daily activity patterns may result in a meaningful benefit to life expectancy.

中文翻译：

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女性和男性体力活动量和强度与模型预期寿命之间的相互作用：前瞻性队列分析


缺乏研究客观测量的体力活动量和强度与预期寿命之间的相互作用。来自英国生物银行的拥有腕戴式加速度计数据的个人也被纳入其中。提取平均加速度和强度梯度来描述身体活动量和强度分布。死亡率数据来自国家登记处。使用参数灵活生存模型估计调整后的预期寿命。包括 40,953 名 (57.1%) 女性（中位年龄 = 61.9 岁）和 30,820 名（42.9%）男性（63.1 岁）。中位随访时间为 6.9 年，共有 1719 人死亡（2.4%）（女性 733 人；男性 986 人）。到 60 岁时，体力活动量和强度越高，预期寿命逐渐延长，在 90 百分位时，女性的预期寿命达到 95.6 岁，男性的预期寿命为 94.5 岁，相当于 3.4（95% 置信区间（95%CI） ）：与第 10 个百分位数相比，女性多活了 2.4–4.4）年，男性多活了 4.6（95%CI：3.6–5.6）年。对于不爱运动的女性，每天多进行 10 分钟或 30 分钟快走，预期寿命分别延长 0.9 年（95% CI：0.5–1.3）和 1.4 年（95% CI：0.9–1.9）；不运动的男性为 1.4 (95% CI: 1.0–1.8) 和 2.5 (95% CI: 1.9–3.1) 年。较高的体力活动量与较长的预期寿命相关，较高的体力活动强度进一步延长了寿命。在日常活动模式中添加哪怕是 10 分钟的快走也可能对预期寿命产生有意义的好处。