The study of human working memory (WM) holds significant importance in neuroscience; yet, exploring the role of the medial temporal lobe (MTL) in WM has been limited by the technological constraints of noninvasive methods. Recent advancements in human intracranial neural recordings have indicated the involvement of the MTL in WM processes. These recordings show that different regions of the MTL are involved in distinct aspects of WM processing and also dynamically interact with each other and the broader brain network. These findings support incorporating the MTL into models of the neural basis of WM. This integration can better reflect the complex neural mechanisms underlying WM and enhance our understanding of WM’s flexibility, adaptability, and precision.

中文翻译：

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重新评估工作记忆中的人类 MTL：来自颅内记录的见解


人类工作记忆 （WM） 的研究在神经科学中具有重要意义;然而，探索内侧颞叶 （MTL） 在 WM 中的作用一直受到无创方法的技术限制。人类颅内神经记录的最新进展表明 MTL 参与 WM 过程。这些记录表明，MTL 的不同区域参与 WM 处理的不同方面，并且还相互动态交互以及与更广泛的大脑网络交互。这些发现支持将 MTL 纳入 WM 神经基础的模型中。这种整合可以更好地反映 WM 背后的复杂神经机制，并增强我们对 WM 的灵活性、适应性和精确性的理解。