INTRODUCTION Lymphocytic esophagitis (LyE) and eosinophilic esophagitis (EoE) are immune-mediated esophageal diseases. Clinical characteristics, endoscopic findings, and treatment outcomes of LyE were compared with EoE. METHODS This was an international retrospective study on adults enrolled at 3 centers in Europe. We recorded clinical characteristics and endoscopy findings at baseline and symptoms, histology, and endoscopy outcomes after treatment of patients with LyE and EoE. RESULTS Demographics, clinical presentation, comorbidities, and endoscopy findings were largely different in 35 patients with LyE compared with 59 patients with EoE. Proton pump inhibitor response was generally lower in LyE. DISCUSSION LyE is clinically different from EoE, but differences in treatment response need further investigation.

中文翻译：

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淋巴细胞性食管炎与嗜酸性粒细胞性食管炎相比的临床特征、内窥镜检查结果和治疗结果。


引言 淋巴细胞性食管炎 （LyE） 和嗜酸性粒细胞性食管炎 （EoE） 是免疫介导的食管疾病。将 LyE 的临床特征、内窥镜检查结果和治疗结局与 EoE 进行比较。方法 这是一项针对欧洲 3 个中心入组的成年人的国际回顾性研究。我们记录了 LyE 和 EoE 患者治疗后的基线临床特征和内窥镜检查结果，以及症状、组织学和内窥镜检查结果。结果 35 例 LyE 患者与 59 例 EoE 患者的人口统计学、临床表现、合并症和内窥镜检查结果存在很大差异。LyE 的质子泵抑制剂反应通常较低。讨论 LyE 在临床上与 EoE 不同，但治疗反应的差异需要进一步研究。