OBJECTIVE To compare the detection rates of hepatic artery digital subtraction angiography (HA-DSA) and magnetic resonance imaging (MRI) gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-DTPA) and MRI gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-EOB-DTPA) for small (diameter ≤2 cm) hepatocellular carcinoma (HCC) lesions. METHODS A prospective analysis of patients admitted to the Tumor Hospital of Guangxi Medical University between January 1, 2015, and December 30, 2016, was conducted. The detection rates of the three methods were analyzed. The diameter of small HCC lesions detected using HA-DSA and MRI-Gd-EOB-DTPA were evaluated. The diagnostic value of HCC Barcelona staging for HA-DSA was analyzed. RESULTS For 107 small lesions detected in 57 patients, the detection rates of HA-DSA and MRI-Gd-DTPA were 86.0% (92/107) and 71.0% (76/107), respectively (p < .05). Of 77 small lesions detected in 42 patients using MRI-Gd-EOB-DTPA and HA-DSA, 67 were detected using HA-DSA, all of which had a rich blood supply, and 72 were detected using MRI-Gd-EOB-DTPA. The minimum diameter of lesions detected using MRI-Gd-EOB-DTPA was approximately 0.4 cm, whereas that of lesions detected using HA-DSA was approximately 0.5 cm. After HA-DSA, a change in the Barcelona staging occurred in 33.3% (62/186) of cases but not after MRI-Gd-DTPA; HA-DSA was significantly better than MRI-Gd-DTPA for staging (p = .03). CONCLUSION HA-DSA and MRI-Gd-EOB-DTPA have high diagnostic values for the detection of small HCC lesions, which is helpful for accurate staging of HCC and provides the most valuable information for patient treatment and prognosis.

中文翻译：

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肝动脉数字减影血管造影在肝细胞癌小病灶检测中的价值。


目的 比较肝动脉数字减影血管造影术 （HA-DSA） 和磁共振成像 （MRI） 二乙烯三胺五乙酸 （MRI-Gd-DTPA） 和 MRI 二乙烯三胺五乙酸钆 （MRI-Gd-EOB-DTPA） 对小 （直径 ≤2 cm） 肝细胞癌 （HCC） 病灶的检出率。方法 对 2015年1月1日至2016年12月30日广西医科大学附属肿瘤医院收治的患者进行前瞻性分析。分析了 3 种方法的检出率。评估使用 HA-DSA 和 MRI-Gd-EOB-DTPA 检测到的小 HCC 病灶的直径。分析 HCC Barcelona 分期对 HA-DSA 的诊断价值。结果 57 例患者中检测到 107 个小病灶，HA-DSA 和 MRI-Gd-DTPA 检出率分别为 86.0% （92/107） 和 71.0% （76/107） （p < .05）。在 42 例患者使用 MRI-Gd-EOB-DTPA 和 HA-DSA 检测到的 77 个小病灶中，使用 HA-DSA 检测到 67 个，所有患者都有丰富的血液供应，使用 MRI-Gd-EOB-DTPA 检测到 72 个。使用 MRI-Gd-EOB-DTPA 检测到的病灶的最小直径约为 0.4 cm，而使用 HA-DSA 检测到的病灶的最小直径约为 0.5 cm。HA-DSA 后，33.3% （62/186） 的病例发生巴塞罗那分期变化，但在 MRI-Gd-DTPA 后没有;HA-DSA 在分期方面显著优于 MRI-Gd-DTPA （p = .03）。结论 HA-DSA和MRI-Gd-EOB-DTPA对HCC小病灶的检测具有较高的诊断价值，有助于HCC的准确分期，为患者治疗和预后提供最有价值的信息。