Repeated exposure to sevoflurane during early developmental stages is a risk factor for social behavioural disorders, but the underlying neuropathological mechanisms remain unclear. As the hippocampal cornu ammonis area 2 subregion (CA2) is a critical centre for social cognitive functions, we hypothesised that sevoflurane exposure can lead to social behavioural disorders by disrupting neuronal activity in the CA2.

中文翻译：

---

出生后反复接触七氟醚会破坏海马 GABA 能神经元活动和发育，从而损害小鼠的社会认知


在早期发育阶段反复接触七氟醚是社会行为障碍的危险因素，但潜在的神经病理学机制仍不清楚。由于海马角氨区 2 亚区 (CA2) 是社会认知功能的关键中心，我们假设七氟烷暴露可通过破坏 CA2 中的神经元活动而导致社会行为障碍。