Powassan virus is a tick-borne flavivirus that can cause severe neuroinvasive disease, with areas of endemicity in the Northeast and Midwest United States, Canada, and Russia. Diagnosis is challenging and relies on a high index of suspicion and choosing the right test based on duration of infection and the patient's immune status. This review covers laboratory testing for Powassan virus, including historical considerations, modern options, and methods being developed in the research space.

中文翻译：

---

Powassan 病毒的实验室检测：过去、现在和未来


Powassan 病毒是一种蜱传黄病毒，可引起严重的神经侵袭性疾病，在美国东北部和中西部、加拿大和俄罗斯流行。诊断具有挑战性，依赖于高度怀疑并根据感染持续时间和患者的免疫状态选择正确的测试。本综述涵盖了 Powassan 病毒的实验室检测，包括历史考虑、现代选择和研究领域正在开发的方法。