Developing a high-sensitive platform for furfuryl mercaptan (FFT) detection is significant but remains challenging. Herein, Au/Ag core-shell nanorods@metal-organic frameworks (Au/Ag@MIL(Fe)) hybrids were constructed through electrostatic interaction, which combined the abundant “hot spots” regions caused by Au/Ag NRs and the great enrichment ability of porous MIL(Fe) and amplified the Raman signal greatly, achieving high sensitivity in FFT solution and volatile gas detection. The enhancement factor (EF) of the Au/Ag@MIL(Fe) substrates reaches 3.96 × 10. The linear detection ranges of FFT solution and gas were 10 - 10 M and 10 −10 ppb, respectively. The LODs were as low as 4.94 × 10 M for solution detection and 77.6 ppb for gas detection and were comparable to HPLC-MS methods. Meanwhile, the Au/Ag@MIL(Fe) hybrids demonstrated favorable reproducibility, stability, selectivity, and successful application for FFT detection in coffee, with a recovery rate from 92.3 % to 108.0 %. The proposed quantitative strategy has significant potential in real food sample analysis.

中文翻译：

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自组装Au/Ag@MIL(Fe)杂化物用于超灵敏SERS检测糠硫醇


开发用于糠硫醇（FFT）检测的高灵敏度平台意义重大，但仍然具有挑战性。在此，通过静电相互作用构建了Au/Ag核壳纳米棒@金属有机框架（Au/Ag@MIL(Fe)）杂化物，该杂化物结合了Au/Ag NRs引起的丰富的“热点”区域和巨大的富集多孔MIL(Fe)的能力并大大放大拉曼信号，在FFT解决方案和挥发性气体检测中实现高灵敏度。 Au/Ag@MIL(Fe)基底的增强因子(EF)达到3.96×10。FFT溶液和气体的线性检测范围分别为10 - 10 M和10 -10 ppb。溶液检测的 LOD 低至 4.94 × 10 M，气体检测的 LOD 低至 77.6 ppb，与 HPLC-MS 方法相当。同时，Au/Ag@MIL(Fe)杂化物表现出良好的重现性、稳定性、选择性，并成功应用于咖啡中的FFT检测，回收率达到92.3%至108.0%。所提出的定量策略在实际食品样品分析中具有巨大潜力。