To study the outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Steven Johnson Syndrome. It was an ambispective, interventional case series conducted at Rajendra Prasad Centre for Ophthalmic Sciences, Delhi, India from 2022 to 2023 evaluating the outcomes of minor salivary gland transplantation with anchorage of the minor salivary glands to superior rectus muscle in twenty cases of severe dry eye disease secondary to chronic Steven-Johnson Syndrome. The pre-operative clinical parameters were compared to those at post-operative 1 year follow-up. At 1 year follow-up, there was an improvement in mean Schirmer-1 value (p = 0.0004), hyperemia score (p = 0.0004), keratinization score (p = 0.04), corneal epithelial defect score (p = 0.0004), corneal opacification score (p = 0.001), corneal neovascularization score (p = 0.001), palisades of Vogt score (p = 0.007), corneal keratinization score (p = 0.04) and corneal conjunctivalization score (p = 0.08). The minor salivary gland transplantation is a viable management option for cases with severe dry eye disease secondary to chronic Steven Johnson Syndrome with clinical improvement in corneal and conjunctival parameters of the ocular surface.

中文翻译：

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小唾液腺移植治疗慢性史蒂文斯-约翰逊综合征继发严重干眼病的临床效果


研究小唾液腺移植治疗继发于慢性史蒂文约翰逊综合症的严重干眼病的结果。这是 2022 年至 2023 年在印度德里 Rajendra Prasad 眼科科学中心进行的一项矛盾的介入性病例系列，评估了 20 例严重干眼症患者小唾液腺锚定于上直肌的小唾液腺移植的结果继发于慢性史蒂文-约翰逊综合症的疾病。将术前临床参数与术后1年随访时的临床参数进行比较。随访 1 年时，平均 Schirmer-1 值 (p = 0.0004)、充血评分 (p = 0.0004)、角化评分 (p = 0.04)、角膜上皮缺损评分 (p = 0.0004)、角膜混浊评分（p = 0.001）、角膜新生血管评分（p = 0.001）、Vogt栅栏评分（p = 0.007）、角膜角化评分（p = 0.04）和角膜结膜化评分（p = 0.08）。对于继发于慢性史蒂文·约翰逊综合征的严重干眼病病例，小唾液腺移植是一种可行的治疗选择，可改善眼表的角膜和结膜参数。