Since 1994, the U.S. Vaccines for Children (VFC) program has covered the cost of vaccines for children whose families might not otherwise be able to afford vaccines. This report assessed and quantified the health benefits and economic impact of routine U.S. childhood immunizations among both VFC-eligible and non-VFC-eligible children born during 1994-2023. Diphtheria and tetanus toxoids and acellular pertussis vaccine; Haemophilus influenzae type b conjugate vaccine; oral and inactivated poliovirus vaccines; measles, mumps, and rubella vaccine; hepatitis B vaccine; varicella vaccine; pneumococcal conjugate vaccine; hepatitis A vaccine; and rotavirus vaccine were included. Averted illnesses and deaths and associated costs over the lifetimes of 30 annual cohorts of children born during 1994-2023 were estimated using established economic models. Net savings were calculated from the payer and societal perspectives. Among approximately 117 million children born during 1994-2023, routine childhood vaccinations will have prevented approximately 508 million lifetime cases of illness, 32 million hospitalizations, and 1,129,000 deaths, at a net savings of $540 billion in direct costs and $2.7 trillion in societal costs. From both payer and societal perspectives, routine childhood vaccinations among children born during 1994-2023 resulted in substantial cost savings. Childhood immunizations continue to provide substantial health and economic benefits, while promoting health equity.

中文翻译：

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儿童疫苗计划时代常规儿童免疫接种的健康和经济效益 - 美国，1994-2023 年。


自 1994 年以来，美国儿童疫苗 (VFC) 计划一直为家庭无力负担疫苗的儿童支付疫苗费用。该报告评估并量化了美国常规儿童免疫接种对 1994 年至 2023 年期间出生的符合 VFC 资格和不符合 VFC 资格的儿童的健康益处和经济影响。白喉和破伤风类毒素和无细胞百日咳疫苗； B型流感嗜血杆菌结合疫苗；口服和灭活脊髓灰质炎病毒疫苗；麻疹、腮腺炎和风疹疫苗；乙型肝炎疫苗；水痘疫苗；肺炎球菌结合疫苗；甲型肝炎疫苗；和轮状病毒疫苗也包括在内。使用既定的经济模型估算了 1994 年至 2023 年期间出生的 30 个年度儿童队列在一生中避免的疾病和死亡以及相关成本。净储蓄是从付款人和社会角度计算的。在 1994 年至 2023 年间出生的约 1.17 亿儿童中，常规儿童疫苗接种将避免约 5.08 亿人终生患病、3200 万人住院和 1,129,000 人死亡，净节省 5400 亿美元的直接成本和 2.7 万亿美元的社会成本。从支付者和社会的角度来看，1994-2023 年出生的儿童定期接种疫苗可以节省大量成本。儿童免疫接种继续提供巨大的健康和经济效益，同时促进健康公平。