Eating behaviour and circadian rhythms are closely related. The type, timing, and quantity of food consumed, and host circadian rhythms, directly influence the intestinal microbiota, which in turn impacts host circadian rhythms and regulates food intake beyond homeostatic eating. This Opinion discusses the impact of food intake and circadian disruptions induced by an obesogenic environment on gut-brain axis signalling. We also explore potential mechanisms underlying the effects of altered gut microbiota on food intake behaviour and circadian rhythmicity. Understanding the crosstalk between gut microbiota, circadian rhythms, and unhealthy eating behaviour is crucial to addressing the obesity epidemic, which remains one of the biggest societal challenges of our time.

中文翻译：

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昼夜节律综合症中的肠道微生物群和饮食行为。


饮食行为与昼夜节律密切相关。摄入食物的类型、时间和数量以及宿主的昼夜节律直接影响肠道微生物群，进而影响宿主的昼夜节律并调节稳态饮食之外的食物摄入量。本意见讨论了致胖环境引起的食物摄入和昼夜节律紊乱对肠脑轴信号传导的影响。我们还探索了肠道微生物群改变对食物摄入行为和昼夜节律影响的潜在机制。了解肠道微生物群、昼夜节律和不健康饮食行为之间的相互作用对于解决肥胖流行问题至关重要，肥胖仍然是我们这个时代最大的社会挑战之一。